Foundation for Women’s Health Promotion and Welfare Initiatives

FWHPWI

Women’s Health is the Health

of the World

FWHPWI 2022 Annual

Conference

WHO has launched a new

framework on breast cancer

More hope of Better Treatment

Option for Breast Cancer

Are blacks more likely to be

diagnosed with late stage

cancer?

Researchers now have improved

understanding of a rare ovarian

tumor

Scientists examined the potent-

ial for cancer treatment in a

compound found in potatoes

and tomatoes

Cervical cancer elimination in

Africa: where are we now and

where do we need to be?

Southern and East African

countries have some of the

highest rates of cervical cancer

in the world. Prof. Lynette

Denny, director of the UCT’s

Gynaecological Cancer Research

Center (GCRC) explains why

Why lung cancer mortality in

South Africa is increasing

SA’s first data on five-year

cancer survival rates released by

Discovery Health

International Agency for

Research on Cancer (IARC) and

Global Initiative for Cancer

Registry Development (CICR)

launch Collaborative Centers to

strengthen cancer surveillances

in Africa

Some plants used in African

traditional medicine to treat

symptoms of cancer show

anticancer properties

Making your health a priority is

easier than you think

Heart-healthy lifestyle linked to

a longer life, free of chronic

health conditions

Racial disparities in use of

preventive measures to thwart

breast cancer

Defensive beliefs likely keep

people from taking at-home

stool tests that screen for

colorectal cancer

Mediterranean lifestyle, not just

diet, may greatly improve health

WHO guidelines and

recommendations provide

details for different age groups

and specific population groups

on how much physical activity is

needed for good health.

Page 1

Dr. F. N. Alaribe Nnadozie,

(MD, FWHPWI)

The 2022 Annual Conference of our foundation

took place on the 10

th

of December 2022.

Theme of the conference: Is cancer prevalence

real in our communities? Key note speaker Dr.

Mabuatsela Maphoru welcomed participants

and highlighted the importance of the

conference theme, not only to the participants

but to our communities and countries as well.

FWHPWI director Dr. FN Alaribe Nnadozie

made a presentation on the theme, showing

Global, African and South African cancer

prevalence and constant increase instead of

reduction. Dr Alaribe Nnadozie also stressed on

the importance of involving scientists so as to

reduce prevalence by constant research

improving diagnostic techniques and therapy.

Guest speaker, Ms Ntombekaya Yalezo in her

speech, informed participants of all the possible

help and support we can give to our fellow

women undergoing cancer treatment. (Some

group pictures below).

The occasion also witnessed presentation of

prizes and appreciation pack to our raffle

winners and guest speakers.

.

August and September also witnessed the

women’s month activities with FWHPWI 2022

inspirational health quotes tree and Outdoor

Tea Time Meeting.

FWHPWI thanks all participants and all our

supporters, especially during the fundraising

for the conference.

.

WHO has launched a new framework on

breast cancer

On February 3, 2023 the World Health

Organization (WHO) published a new Global

Breast Cancer Initiative Framework (GBCI),

aimed at saving 2.5 million lives from breast

cancer by 2040. The new Framework recom-

mends to countries to implement the three

pillars of health promotion for early

detection, timely diagnosis and compre-

hensive management of breast cancer to

reach the targets.

HPV

OVERVIEW/SYMPTOMS

HPV is the most common

sexually transmitted infection.

Many people with HPV

don't develop any symp-

tom but can still infect

others through sexual

contact.

Symptoms may include

warts on the genitals or

sur-rounding skin.

There's no cure for the

virus and warts may go

away on their own.

Treatment focuses on

removing the warts.

A vaccine that prevents

the HPV strains most

likely to cause genital

warts and cervical cancer

is recomm-ended for boys

and girls.

Cancer is a leading

cause of premature

death in every

country in the world

But many of these

deaths can be

prevented

Click to join us

share information about the cancers

Page 2

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More hope of Better Treatment Option for

Breast Cancer

A new clinical trial has found that

combination of targeted drug ribociclib

(Kisqali) and hormone therapy better halts

the growth of aggressive tumors that have

spread in the body than standard treat-

ment with a combination of chemotherapy

drugs. It is reported that “women who

received the ribociclib–hormone therapy

combination lived for twice as long without

their cancer getting worse, a measure

called progression-free survival. They also

had far fewer side effects.”

Are blacks more likely to be diagnosed

with late-stages cancer?

According to a recent research from Cancer

Research UK and NHS Digital, Black women

from Caribbean and African backgrounds are

more likely to be diagnosed with certain

types of cancer at later stages (3 or 4), when

treatment is less likely to be successful.

The study is the first to show that ethnicity is

a significant factor in late-stage diagnosis for

women with breast, ovarian, uterine, non-

small cell lung cancer and colon cancer, and

for men with prostate cancer.

Researchers now have improved under-

standing of a rare ovarian tumor

Ovarian granulosa cell tumor is a rare type of

ovarian cancer that affects the ovaries and

fallopian tubes, and can extend further into

the pelvis and lymph nodes. Researchers at

Hokkaido University have analyzed the

disease and treatment of hundreds of women

with ovarian granulosa cell tumors and say

more invasive surgery could be avoided in

some cases. The findings, published in the

journal Gynecologic Oncology, improve

understanding of how the disease progresses

and responds to therapy.

.

Scientists examined the potential for

cancer treatment in a compound found in

potatoes and tomatoes

Recently, researchers reviewed studies that

looked at the anticancer properties of plants

like tomatoes and potatoes, which are found

in the nightshade family. The review

highlights the range of in silico, in vitro, and

in vivo studies done on the compounds.

The analysis demonstrates that glycoalkaloid

compounds of the plants target numerous

cellular pathways, which could be used to

target specific mechanisms in cancer cells.

According to the researchers, glycoalkaloid

compounds could be used in conjunction with

other cancer treatments, to broaden the scope

of their effectiveness.

Page 3

Just a few ways to

reduce your risk of

gynaecological cancers

advised by

National Foundation

for Cancer Research

Have your Pap test

by age 21

The Pap test looks for abnormal

cell changes in the cervix to

detect cervical cancer in its early

stages.

Protect yourself from

Human papilloma

virus (HPV)

Talk to your doctor about

getting the HPV test and HPV

vaccine. Also, limit your sexual

partners and, when you do have

sex, use a condom.

Don’t smoke.

Smoking increases the risk of

different cancers including

cervical, ovarian, vaginal and

vulvar cancers.

Make healthy

choices.

It’s important to maintain a

healthy weight, be active and eat

a healthy diet consisting of fruit,

vegetables, lean proteins and

whole grains.

Share your family

history with your

doctor.

Genetic testing is now available

to see if you carry a BRCA1 or

BRCA2 mutation, which could

put you in a high-risk category

for ovarian and breast cancer. If

you carry a genetic mutation

associated to Lynch Syndrome,

a heredity condition that

increases your risk of colon

cancer, ovarian cancer, uterine

cancer, etc.

Contact your doctor

if you notice any of

these symptoms.

Abnormal vaginal

bleeding or discharge

Pelvic pain or

pressure

Abdominal or back

pain

Bloating

Changes in bathroom

habits (increased

urination, constipation,

diarrhea)

Itching or burning of

the vulva

Changes in vulva

color or skin (rash,

sores, warts, ulcers).

nfcr.org/

TOMATOES

Image Credit: freshfruitportal.com/news/

POTATOES

Image credit: bcfresh.ca/potatoes/

Cervical cancer elimination in Africa:

where are we now and where do we need

to be?

A new report from the Union for

International Cancer Control (UICC)

provides insights into the current situation of

the cervical cancer burden in Africa, as well

as recommendations to improve access to

care and meet the cervical cancer elimination

targets set by World Health Organization

(WHO).

“Elimination” means that

a country records fewer than four cases of

cervical cancer for 100,000 people; in Sub-

Saharan Africa, incidence rates are currently

more than ten times higher.

Southern and East African countries have

some of the highest rates

1

of cervical

cancer in the world. Prof Lynette Denny,

director of the UCT's Gynaecological

Cancer Research Centre (GCRC) explains

why

According to Prof. Denny, it’s due to a

complex melange of reasons. For instance,

there’s a very strong connection with

poverty, with high numbers of people living

in unsatisfactory conditions, as well as fragile

healthcare systems that tend to focus on

curative rather than preventative interven-

tions, because there is such a high burden of

disease. Access to healthcare is very limited

for women over the age of 30, with virtually

no successful screening programmes.

Why Lung cancer mortality in South

Africa is increasing

As much as we are still in a pandemic, lung

cancer remains one of those insidious

diseases that don’t get diagnosed even when

symptoms show up. When someone coughs,

lung cancer is never the first thought. Most

people tend to attribute it to an allergy,

asthma, cold, or flu and try to bear with it

until the cough ‘goes away’.

people tend to attribute it to an allergy,

asthma, cold, or flu and try to bear with it

until the cough ‘goes away’.

SA's first data on five-year cancer survival

rates released by Discovery Health

One of the first things most people diagnosed

with cancer want to understand is their

estimated survival rate. Until now, there

hasn't been publicly available information on

this front specific to South Africa's

population. We share the first localised data

on five-year cancer survival rates (in

Discovery Health's privately insured

population), across the four most common

cancer types.

International Agency for Research on

Cancer (IARC) and Global Initiative for

Cancer Registry Development (GICR)

launch Collaborating Centers to streng-

then cancer Surveillance in Africa

Against the backdrop of an increasing cancer

burden in Africa and limited data to help

direct government resources for prevention

and treatment, three Collaborating Centers

were opened in Kenya, South Africa and Côte

d’Ivoire to strengthen cancer registration

across the continent. Established within the

framework of the GICR, these Collaborating

Centers were launched by the IARC and

partners in Nairobi, Johannesburg and

Abidjan. The first of the IARC-GICR

Collaborating Centers was launched in

November 2022 at the Nairobi Cancer

Registry, which is within the Population

Health and Surveillance Division of

the Kenya Medical Research Institute

(KEMRI).

Page 4

Cancer News: Africa

The cancer burden is

expected to nearly

double in sub-Saharan

Africa during the next

20 years as a result of

population growth and

ageing, reaching 1.5

million new cases and

1 million deaths

by 2040.

To overcome this

mounting challenge,

each country in sub-

Saharan Africa needs

to implement a cancer

control programme as

part of national health

planning and to have

at its disposal routine

surveillance systems

capable of monitoring

progress in the

delivery of specific

interventions.

IARC/WHO PRESS

RELEASE

10 May 2022

Some plants used in African traditional

medicine to treat symptoms of cancer show

anticancer properties.

The rich flora of Africa results from a vast

difference in environmental and climatic

conditions such as deserts, savannah, and

tropical rain forests. Some anticancer plants

that are native to Africa have been used in

traditional medicine to treat symptoms of

cancer. Below are some plants - native to

Africa, with extracts that have shown

anticancer properties

a) Portulaca oleracea: often referred to as

Purslane, and abundant in most regions of

Africa – belongs to the genus Portulaca in the

family Portulacaceae. The polysaccharides

of P. oleracea L., POL-P3b, have shown

inhibition of tumors by means of cell cycle

arrest, elicitation of DNA damage and

induction of apoptosis.

b) Withania somnifera: a small, bushy,

evergreen shrub widely distributed across the

world and abundant in South Africa and

Botswana. It is a member of the Solanaceae

family. It has been shown that W.

somnifera root extracts can inhibit vimentin,

a protein normally found in regions of

metastasis, thus suggesting its counteracting

effects on tumour formation.

c) Cajanus cajan: a medicinal plant that is

native to the Southwest of Nigeria. It is

grown for food in Nigeria. Cajanol is derived

from Cajanol cajan roots and has a multitude

of pharmacological activities such as anti-

tumor properties. Cajanol inhibits NF-κB

phosphorylation and nuclear ectopia by

interfering with PI3K expression and the

phosphorylation of Akt.

Page 5

Do you know?

A scientist at Jackson

State University in

Mississippi

obtained a US patent

(6,849,604, issued

1 Feb 2005)

on extracts of

Vernonia amygdalina,

an African medicinal

plant sometimes

called Bitterleaf (or

Bitter Leaf).

According to the

patent, the extracts

are effective against

cancer.

The inventor

obtained samples in

Benin City, Nigeria.

A

B

C

A) PORTULACA OLERACEA

Image credit: plantinfo.co.za

B) WITHANIA SOMNIFERA

Image credit: pza.sanbi.org

C) CAJANUS CAJAN

Image credit: plantinfo.co.za

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Making your health a priority is easier

than you think

Making your everyday health a priority

shouldn’t add extra pressure to your day or

time. And with more convenient home gym

and diet options available than ever before,

it’s never been easier to get started on your

journey towards a healthier lifestyle.

Heart-healthy lifestyle linked to a longer

life, free of chronic health conditions

In June 2022, the American Heart

Association updated the metrics for optimal

cardiovascular health to include sleep –

Life’s Essentials 8. The tool measures 4

indicators related to cardiovascular and

metabolic health status (blood pressure,

cholesterol, blood sugar and blood mass

index); and 4 behaviour/lifestyle factors

(smoking status, physical activity, sleep and

diet). Two new studies by related research

groups have found that adults who live a

heart-healthy lifestyle, as measured by the

American Heart Association's Life's

Essential 8 (LE8) cardiovascular health

scoring, tend to live longer lives free of

chronic disease.

Racial disparities in use of preventive

measures to thwart breast cancer

A study from researchers at The Ohio State

University provides insights into the factors

that contribute to racial disparities in use of

preventive measures, including genetic

testing, prophylactic mastectomies and

medication to thwart breast cancer. Among

their findings: Black women may be less

focused on breast cancer risk as an issue to be

addressed proactively, may less frequently

possess information to help guide their

decisions about prevention, and face more

constraints when it comes to making and

carrying out health-protective decisions.

constraints when it comes to making and

carrying out health-protective decisions.

Defensive beliefs likely keep people from

taking at-home stool tests that screen for

colorectal cancer

Colorectal cancer is one of the most treatable

cancers, especially if it is detected early;

however, many people do not undergo

recommended screening, even despite the

availability of at-home stool fecal

immunochemical test (FIT) kits. A new

research reveals that people who react

defensively to the invitation to get screened

are less likely to take part.

Mediterranean lifestyle, not just diet, may

greatly improve health

Much is known about the heart-health

benefits of adopting a Mediterranean-style

diet, with its heavy focus on whole grains,

fruits, vegetables, fish and healthy oils. But

what about the rest of the Mediterranean

lifestyle?

WHO guidelines and recommendations

provide details for different age groups

and specific population groups on how

much physical activity is needed for good

health.

WHO defines physical activity as any bodily

movement produced by skeletal muscles that

requires energy expenditure. Physical

activity refers to all movement including

during leisure time, for transport to get to and

from places, or as part of a person’s work.

Both moderate- and vigorous-intensity

physical activity improve health. How much

of physical activity is recommended?

HEALTH AND LIFESTYLE

Page 6

The COVID-19

pandemic is not over.

Never

forget this practice!

It is necessary

for your health

now and always.

Do it often.

The best for you is to

keep safe for yourself

and for us all.

Click here to Donate

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Ingredients

 1 soursop fruit, peeled and cut into chunks

 1 ½ cups milk, or to taste

 2 tablespoons white sugar, or to taste

 2 teaspoons vanilla extract

 ½ teaspoon ground cinnamon

Directions: 1. Working in batches, press soursop

pieces through a fine-mesh strainer with the back of a

spoon into a bowl to remove the juice from the fruit.

2. Whisk milk, sugar, vanilla, cinnamon, and nutmeg

into soursop juice until sugar is dissolved completely.

Pour punch into a pitcher and refrigerate until chilled,

at least 30 minutes.

Source:Read more

Soursop is a common name for the fruit of the Annona

muricata tree. The dark green, prickly, heart shaped fruit grows in

tropical and subtropical regions of the world.

Laboratory studies indicate that leaf extracts from the plant are

cytotoxic to cells in different types of cancer,

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